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Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Frontiers of Medicine   Pages 939-956 doi: 10.1007/s11684-023-0987-9

Abstract: A small proportion of mononuclear diploid cardiomyocytes (MNDCMs), with regeneration potential, couldTo this end, 12 645 cardiac cells were generated from embryonic day 17.5 and postnatal days 2 and 8 miceThree cardiac developmental paths were identified: two switching to cardiomyocytes (CM) maturation withThese findings could improve the understanding of MNDCM heterogeneity and cardiac development, thus providingnew clues for approaches to effective cardiac regeneration.

Keywords： mononuclear diploid cardiomyocytes     cell–cell communication     cardiac fibroblast     single-cell RNA sequencing     cardiac regeneration    

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Integrated management of cardiac failure: the cardiac failure clinic

Daniel LOISANCE

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 20-25 doi: 10.1007/s11684-011-0106-1

Abstract:

The prevalence of the risk factors and the risk of cardiac failure are both increasing in China.The wide range of clinical presentations of cardiac failure (acute or chronic) and of therapeutic approachesintegration within the same structure of the various experts involved in the diagnosis and the treatment of cardiacIn these centers, collaboration should replace competition between the medical and the surgical cardiac

Keywords： cardiac failure     cardiac transplantation     mechanical circulatory support    

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Application of Biomaterials in Cardiac Repair and Regeneration Review

Zhi Cui,Baofeng Yang,Ren-Ke Li

Engineering 2016, Volume 2, Issue 1,   Pages 141-148 doi: 10.1016/J.ENG.2016.01.028

Abstract: Biomaterials, both natural and synthetic, exhibit great potential in cardiac repair and regeneration,

Keywords： Myocardial infarction     Heart regeneration     Biomaterial     Tissue engineering     Stem cell    

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Association of cardiac disease with the risk of post-lung transplantation mortality in Chinese recipients

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 58-67 doi: 10.1007/s11684-022-0937-y

Abstract: Kaplan–Meier estimates showed that recipients with cardiac abnormalities had a significantly increasedAfter adjusting for potential confounders, cardiac abnormality was shown to be independently associated

Keywords： cardiac disease     mortality     aged population     lung transplantation    

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Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 254-258 doi: 10.1007/s11684-014-0319-1

Abstract: Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which

Keywords： mantle cell lymphoma     bendamustine     cardiogenic shock    

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Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 19-24 doi: 10.1007/s11684-008-0005-2

Abstract: the effects of RNA interference (RNAi) targeting angiotensin 1a receptor (AT1a) on blood pressure and cardiactargeting AT1a receptor inhibits the development of renovascular hypertension and the accompanying cardiac

Keywords： therapy     Sprague     administration     cardiac hypertrophy     valsartan    

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Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 445-455 doi: 10.1007/s11684-014-0378-3

Abstract: The purpose of this study was to investigate the effects of PDE5 inhibitor on cardiac fibrosis.In control mice, 4 weeks of TAC induced significant cardiac dysfunction, cardiac fibrosis, and cardiacSildenafil treatment markedly prevented TAC-induced cardiac dysfunction, cardiac fibrosis and cardiacIn isolated cardiac fibroblasts, sildenafil blocked TGF-β1-induced cardiac fibroblast transformationthrough CREB activation in cardiac fibroblasts.

Keywords： PDE5     cardiac fibrosis     TGF-β     CREB    

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Migration of manganese and iron during the adsorption-regeneration cycles for arsenic removal

Fangfang CHANG, Jiuhui QU, Xu ZHAO, Wenjun LIU, Kun WU

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 4,   Pages 512-518 doi: 10.1007/s11783-011-0372-9

Abstract: Fe-Mn binary oxide incorporated into porous diatomite (FMBO-diatomite) was prepared in situ and regenerated in a fixed-bed column for arsenite [As(III)] and arsenate [As(V)] removal. Four consecutive adsorption cycles were operated under the following conditions: Initial arsenic concentration of 0.1 mg·L , empty bed contact time of 5 min, and pH 7.0. About 3000, 3300, 3800, and 4500 bed volumes of eligible effluent (arsenic concentration≤0.01 mg·L ) were obtained in four As(III) adsorption cycles; while about 2000, 2300, 2500, and 3100 bed volumes of eligible effluent were obtained in four As(V) adsorption cycles. The dissection results of FMBO-diatomite fixed-bed exhibited that small amounts of manganese and iron were transferred from the top of the fixed-bed to the bottom of the fixed-bed during As(III) removal process. Compared to the extremely low concentration of iron (<0.01 mg·L ), the fluctuation concentration of Mn in effluent of the As(III) removal column was in a range of 0.01–0.08 mg·L . The release of manganese suggested that manganese oxides played an important role in As(III) oxidation. Determined with the US EPA toxicity characteristic leaching procedure (TCLP), the leaching risk of As(III) on exhausted FMBO-diatomite was lower than that of As(V).

Keywords： arsenic     adsorption     filtration     regeneration     fixed-bed    

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biomaterial transplantation and genetic enhancement of intrinsic growth capacities to promote CNS axon regeneration

Bin Yu, Xiaosong Gu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 131-137 doi: 10.1007/s11684-018-0642-z

Abstract: The inhibitory environment that surrounds the lesion site and the lack of intrinsic regenerative capacity of the adult mammalian central nervous system (CNS) impede the regrowth of injured axons and thereby the reestablishment of neural circuits required for functional recovery after spinal cord injuries (SCI). To circumvent these barriers, biomaterial scaffolds are applied to bridge the lesion gaps for the regrowing axons to follow, and, often by combining stem cell transplantation, to enable the local environment in the growth-supportive direction. Manipulations, such as the modulation of PTEN/mTOR pathways, can also enhance intrinsic CNS axon regrowth after injury. Given the complex pathophysiology of SCI, combining biomaterial scaffolds and genetic manipulation may provide synergistic effects and promote maximal axonal regrowth. Future directions will primarily focus on the translatability of these approaches and promote therapeutic avenues toward the functional rehabilitation of patients with SCIs.

Keywords： spinal cord injury     biomaterial     extrinsic barrier     intrinsic regeneration capacity    

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Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 401-413 doi: 10.1007/s11684-011-0161-7

Abstract: science and tissue engineering technology, is considered as an ideal alternative strategy for bone regenerationThe preclinical animal models for bone regeneration and the key translational points to clinical success

Keywords： bone regeneration     animal models     translational strategies     oral and maxillofacial region    

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Investigation on regeneration and energy storage characteristics of a solar liquid desiccant air-conditioning

SHI Mingheng, DU Bin, ZHAO Yun

Frontiers in Energy 2007, Volume 1, Issue 1,   Pages 85-90 doi: 10.1007/s11708-007-0008-8

Abstract: In this paper regeneration and energy storage characteristics were studied theoretically and experimentallyTwo criterion equations for heat and mass transfer in the regeneration process were obtained.The main factors that influence the regeneration process were analyzed.

Keywords： desiccant air-conditioning     regeneration process     air-conditioning system     energy     regeneration    

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Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 2,   Pages 265-278 doi: 10.1007/s11465-019-0571-9

Abstract: To improve the fuel economy of rail vehicles, this study presents the feasibility of using power regenerating dampers (PRDs) in the primary suspension systems of railway vehicles and evaluates the potential and recoverable power that can be obtained. PRDs are configured as hydraulic electromagnetic-based railway primary vertical dampers and evaluated in parallel and series modes (with and without a viscous damper). Hydraulic configuration converts the linear behavior of the track into a unidirectional rotation of the generator, and the electromagnetic configuration provides a controllable damping force to the primary suspension system. In several case studies, generic railway vehicle primary suspension systems that are configured to include a PRD in the two configuration modes are modeled using computer simulations. The simulations are performed on measured tracks with typical irregularities for a generic UK passenger route. The performance of the modified vehicle is evaluated with respect to key performance indicators, including regenerated power, ride comfort, and running safety. Results indicate that PRDs can simultaneously replace conventional primary vertical dampers, regenerate power, and exhibit desirable dynamic performance. A peak power efficiency of 79.87% is theoretically obtained in series mode on a top-quality German Intercity Express track (Track 270) at a vehicle speed of 160 mile/h (~257 km/h).

Keywords： railway vehicle     primary damper     power regeneration     ride comfort     running safety    

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Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 237-249 doi: 10.1007/s11684-016-0464-9

Abstract: In this regard, Wnt and Notch signaling has gained increased research attention in hair cell regenerationpossibilities of controlling these pathways with the hair cell fate determiner Atoh1 to regulate hair cell regeneration

Keywords： inner ear     cochlea     hair cell     regeneration     Wnt     Notch     signaling pathways    

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Electro-assisted regeneration of ion exchange resins

LIU Zhigang, WANG Ying, LI Yansheng, CHANG Hui

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 4,   Pages 410-414 doi: 10.1007/s11783-008-0069-x

Abstract: Electro-assisted regeneration (EAR) for the mixed bed of strongly acidic cation and weakly basic anionExperimental results showed that the efficiency of resin regeneration was strictly dependent on the voltage, regeneration time, and feed regenerant flow rate.The desalination and regeneration reaction mechanisms of the mixed resins indicated the regeneration

Keywords： effluent volume     acidic     three-compartment     weakly     exchange    

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Sulfidation/regeneration multicycle testing of nickel-modified ZnFe

Wei LI, Jinju GUO, Jiejie HUANG, Jiaotao ZHAO

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 4,   Pages 435-440 doi: 10.1007/s11705-010-0506-9

Abstract: desulphurization reactivity, mechanical strength, ability to regenerate, and stability to endure many sulfidation-regenerationmeasured in a fixed-bed reactor at middle temperature of 300°C (sulfidation temperature) and 500°C (regenerationnickel-modified ZnFe O keeps high reactivity and structural stability in the multicycle testing of sulfidation/regeneration

Keywords： hot gas desulphurization     nickel-modified ZnFe2O4     sulfidation/regeneration    

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Title Author Date Type Operation

Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Journal Article

Integrated management of cardiac failure: the cardiac failure clinic

Daniel LOISANCE

Journal Article

Application of Biomaterials in Cardiac Repair and Regeneration

Zhi Cui,Baofeng Yang,Ren-Ke Li

Journal Article

Association of cardiac disease with the risk of post-lung transplantation mortality in Chinese recipients

Journal Article

Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu

Journal Article

Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Journal Article

Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Journal Article

Migration of manganese and iron during the adsorption-regeneration cycles for arsenic removal

Fangfang CHANG, Jiuhui QU, Xu ZHAO, Wenjun LIU, Kun WU

Journal Article

biomaterial transplantation and genetic enhancement of intrinsic growth capacities to promote CNS axon regeneration

Bin Yu, Xiaosong Gu

Journal Article

Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Journal Article

Investigation on regeneration and energy storage characteristics of a solar liquid desiccant air-conditioning

SHI Mingheng, DU Bin, ZHAO Yun

Journal Article

Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Journal Article

Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Journal Article

Electro-assisted regeneration of ion exchange resins

LIU Zhigang, WANG Ying, LI Yansheng, CHANG Hui

Journal Article

Sulfidation/regeneration multicycle testing of nickel-modified ZnFe

Wei LI, Jinju GUO, Jiejie HUANG, Jiaotao ZHAO

Journal Article